Click on the table headers to sort. Stats are explained at the Advanced NFL Stats glossary page.
| Rank | Player | Team | G | WPA | EPA | WPA/G | EPA/P | SR(%) | Att | Yds | YPC | RushTDs | Rec | RecYds | RecTDs |
| 1 | 27-R.Rice | BLT | 16 | 1.45 | 23.8 | 0.09 | 0.06 | 44.2 | 254 | 1339 | 5.3 | 7 | 78 | 702 | 1 |
| 2 | 28-C.Johnson | TEN | 16 | 1.33 | 49.7 | 0.08 | 0.11 | 38.6 | 358 | 2006 | 5.6 | 14 | 50 | 503 | 2 |
| 3 | 32-M.Jones-Drew | JAX | 16 | 1.18 | 9.0 | 0.07 | 0.02 | 40.4 | 312 | 1391 | 4.5 | 15 | 53 | 374 | 1 |
| 4 | 26-C.Wells | ARZ | 16 | 0.92 | 1.3 | 0.06 | 0.01 | 43.1 | 176 | 793 | 4.5 | 7 | 12 | 143 | 0 |
| 5 | 28-F.Jones | DAL | 14 | 0.88 | 4.0 | 0.06 | 0.03 | 38.7 | 116 | 685 | 5.9 | 3 | 19 | 119 | 0 |
| 6 | 28-J.Stewart | CAR | 16 | 0.88 | 22.9 | 0.06 | 0.09 | 45.4 | 221 | 1133 | 5.1 | 10 | 18 | 139 | 1 |
| 7 | 29-J.Addai | IND | 15 | 0.87 | 8.8 | 0.06 | 0.03 | 45.3 | 219 | 828 | 3.8 | 10 | 51 | 336 | 3 |
| 8 | 34-D.Williams | CAR | 13 | 0.79 | 6.6 | 0.06 | 0.03 | 41.4 | 216 | 1117 | 5.2 | 7 | 29 | 252 | 0 |
| 9 | 23-W.McGahee | BLT | 15 | 0.76 | 13.1 | 0.05 | 0.10 | 45.9 | 109 | 544 | 5.0 | 12 | 15 | 85 | 2 |
| 10 | 25-R.Bush | NO | 12 | 0.67 | 6.8 | 0.06 | 0.06 | 47.3 | 51 | 293 | 5.7 | 5 | 38 | 272 | 1 |
| 11 | 21-F.Gore | SF | 14 | 0.65 | 17.3 | 0.05 | 0.06 | 37.7 | 229 | 1120 | 4.9 | 10 | 52 | 406 | 3 |
| 12 | 25-J.Charles | KC | 15 | 0.48 | 13.8 | 0.03 | 0.05 | 43.1 | 190 | 1120 | 5.9 | 7 | 40 | 297 | 1 |
| 13 | 43-L.Weaver | PHI | 16 | 0.46 | 9.4 | 0.03 | 0.10 | 40.4 | 70 | 323 | 4.6 | 2 | 15 | 140 | 2 |
| 14 | 21-R.Moats | HST | 8 | 0.40 | -0.2 | 0.05 | 0.00 | 46.6 | 101 | 390 | 3.9 | 4 | 13 | 106 | 1 |
| 15 | 43-D.Sproles | SD | 16 | 0.39 | 14.8 | 0.02 | 0.09 | 43.9 | 93 | 343 | 3.7 | 3 | 45 | 497 | 4 |
| 16 | 31-D.Brown | IND | 11 | 0.35 | 3.8 | 0.03 | 0.04 | 44.4 | 78 | 281 | 3.6 | 3 | 11 | 169 | 0 |
| 17 | 34-S.Morris | NE | 12 | 0.35 | 4.2 | 0.03 | 0.04 | 44.0 | 73 | 319 | 4.4 | 2 | 19 | 180 | 0 |
| 18 | 21-M.Bell | NO | 13 | 0.35 | -8.9 | 0.03 | -0.05 | 42.5 | 172 | 654 | 3.8 | 5 | 4 | 12 | 0 |
| 19 | 25-R.Grant | GB | 16 | 0.32 | 16.2 | 0.02 | 0.05 | 40.7 | 282 | 1253 | 4.4 | 11 | 25 | 197 | 0 |
| 20 | 23-T.Choice | DAL | 15 | 0.30 | 8.6 | 0.02 | 0.09 | 45.3 | 64 | 349 | 5.5 | 3 | 15 | 132 | 0 |
| 21 | 20-J.Forsett | SEA | 16 | 0.22 | 10.2 | 0.01 | 0.06 | 46.0 | 114 | 619 | 5.4 | 4 | 41 | 350 | 1 |
| 22 | 29-C.Taylor | MIN | 16 | 0.21 | 2.0 | 0.01 | 0.01 | 37.3 | 93 | 332 | 3.6 | 1 | 44 | 389 | 1 |
| 23 | 28-A.Peterson | MIN | 16 | 0.21 | 0.1 | 0.01 | 0.00 | 40.9 | 315 | 1389 | 4.4 | 18 | 43 | 436 | 0 |
| 24 | 24-M.Barber | DAL | 15 | 0.19 | -9.4 | 0.01 | -0.04 | 43.2 | 214 | 932 | 4.4 | 7 | 26 | 221 | 0 |
| 25 | 46-L.Betts | WAS | 10 | 0.17 | 8.4 | 0.02 | 0.11 | 40.5 | 56 | 210 | 3.8 | 2 | 17 | 179 | 0 |
| 26 | 32-C.Benson | CIN | 12 | 0.16 | -14.1 | 0.01 | -0.05 | 37.1 | 264 | 1062 | 4.0 | 5 | 17 | 111 | 0 |
| 27 | 23-S.Greene | NYJ | 13 | 0.16 | 2.7 | 0.01 | 0.02 | 37.9 | 109 | 541 | 5.0 | 2 | 0 | 0 | 0 |
| 28 | 23-R.Brown | MIA | 9 | 0.15 | 11.2 | 0.02 | 0.06 | 46.1 | 147 | 648 | 4.4 | 8 | 14 | 98 | 0 |
| 29 | 33-L.McClain | BLT | 16 | 0.12 | 4.4 | 0.01 | 0.06 | 51.4 | 46 | 180 | 3.9 | 2 | 21 | 141 | 0 |
| 30 | 35-Q.Ganther | WAS | 8 | 0.11 | -1.1 | 0.01 | -0.02 | 44.6 | 62 | 199 | 3.2 | 3 | 9 | 99 | 0 |
| 31 | 29-L.McCoy | PHI | 16 | 0.10 | -10.2 | 0.01 | -0.05 | 41.7 | 155 | 637 | 4.1 | 4 | 40 | 308 | 0 |
| 32 | 32-K.Bell | CHI | 7 | 0.10 | -0.6 | 0.01 | -0.01 | 31.8 | 40 | 220 | 5.5 | 0 | 1 | 4 | 0 |
| 33 | 34-Kv.Smith | DET | 3 | 0.09 | 0.5 | 0.03 | 0.01 | 39.4 | 55 | 204 | 3.7 | 1 | 12 | 80 | 0 |
| 34 | 44-J.Snelling | ATL | 14 | 0.08 | 9.8 | 0.01 | 0.05 | 40.8 | 142 | 613 | 4.3 | 4 | 30 | 259 | 1 |
| 35 | 24-C.Williams | TB | 16 | 0.08 | -17.0 | 0.01 | -0.07 | 36.9 | 209 | 816 | 3.9 | 4 | 29 | 219 | 3 |
| 36 | 22-F.Jackson | BUF | 15 | 0.07 | -5.7 | 0.00 | -0.02 | 44.8 | 229 | 1027 | 4.5 | 2 | 42 | 351 | 2 |
| 37 | 34-R.Williams | MIA | 16 | 0.06 | 16.7 | 0.00 | 0.06 | 44.6 | 241 | 1121 | 4.7 | 11 | 35 | 264 | 2 |
| 38 | 37-A.Foster | HST | 4 | 0.06 | 7.8 | 0.02 | 0.12 | 55.6 | 54 | 257 | 4.8 | 3 | 8 | 93 | 0 |
| 39 | 21-L.Tomlinson | SD | 14 | 0.05 | -22.7 | 0.00 | -0.09 | 37.2 | 223 | 730 | 3.3 | 12 | 20 | 154 | 0 |
| 40 | 34-R.Mendenhall | PIT | 15 | 0.04 | 1.9 | 0.00 | 0.01 | 40.9 | 242 | 1108 | 4.6 | 7 | 25 | 261 | 1 |
| 41 | 33-M.Turner | ATL | 11 | 0.04 | 8.2 | 0.00 | 0.04 | 39.2 | 178 | 871 | 4.9 | 10 | 5 | 35 | 0 |
| 42 | 32-E.James | SEA | 7 | 0.03 | -2.9 | 0.00 | -0.06 | 34.0 | 46 | 125 | 2.7 | 0 | 3 | 19 | 0 |
| 43 | 20-T.Jones | NYJ | 16 | 0.02 | -3.4 | 0.00 | -0.01 | 38.1 | 332 | 1402 | 4.2 | 14 | 10 | 58 | 0 |
| 44 | 23-R.Jennings | JAX | 15 | 0.02 | 2.5 | 0.00 | 0.04 | 42.1 | 39 | 202 | 5.2 | 1 | 16 | 101 | 0 |
| 45 | 23-P.Thomas | NO | 14 | 0.02 | 17.7 | 0.00 | 0.09 | 47.5 | 147 | 793 | 5.4 | 6 | 39 | 302 | 2 |
| 46 | 36-B.Westbrook | PHI | 8 | 0.01 | 3.7 | 0.00 | 0.04 | 41.8 | 61 | 274 | 4.5 | 1 | 25 | 181 | 1 |
| 47 | 39-L.Maroney | NE | 15 | 0.00 | -1.0 | 0.00 | 0.00 | 47.0 | 194 | 757 | 3.9 | 9 | 14 | 99 | 0 |
| 48 | 34-A.Green | GB | 7 | -0.01 | -2.9 | 0.00 | -0.06 | 39.1 | 41 | 160 | 3.9 | 1 | 3 | 18 | 0 |
| 49 | 31-R.Cartwright | WAS | 11 | -0.02 | -6.4 | 0.00 | -0.07 | 40.8 | 64 | 228 | 3.6 | 0 | 27 | 242 | 2 |
| 50 | 28-B.Scott | CIN | 8 | -0.02 | 1.1 | 0.00 | 0.01 | 39.0 | 68 | 304 | 4.5 | 0 | 4 | 53 | 0 |
| 51 | 32-J.Norwood | ATL | 10 | -0.02 | -8.6 | 0.00 | -0.08 | 36.5 | 76 | 252 | 3.3 | 0 | 19 | 186 | 1 |
| 52 | 29-M.Bush | OAK | 15 | -0.05 | -9.7 | 0.00 | -0.07 | 37.8 | 123 | 589 | 4.8 | 3 | 17 | 105 | 0 |
| 53 | 34-C.Jennings | CLV | 9 | -0.10 | -9.8 | -0.01 | -0.13 | 35.9 | 63 | 220 | 3.5 | 1 | 9 | 56 | 0 |
| 54 | 28-M.Morris | DET | 14 | -0.10 | 0.0 | -0.01 | 0.00 | 39.6 | 93 | 384 | 4.1 | 2 | 26 | 210 | 0 |
| 55 | 22-J.Jones | SEA | 14 | -0.12 | -15.0 | -0.01 | -0.07 | 39.2 | 177 | 663 | 3.7 | 2 | 35 | 232 | 2 |
| 56 | 34-K.Smith | DET | 10 | -0.13 | -6.4 | -0.01 | -0.03 | 39.4 | 162 | 543 | 3.4 | 3 | 28 | 329 | 1 |
| 57 | 28-C.Buckhalter | DEN | 14 | -0.15 | 1.2 | -0.01 | 0.01 | 50.0 | 120 | 642 | 5.4 | 1 | 31 | 240 | 0 |
| 58 | 29-L.Washington | NYJ | 7 | -0.15 | -10.5 | -0.02 | -0.10 | 39.6 | 71 | 330 | 4.6 | 0 | 15 | 131 | 0 |
| 59 | 33-K.Faulk | NE | 15 | -0.18 | 0.5 | -0.01 | 0.00 | 45.5 | 62 | 335 | 5.4 | 2 | 37 | 301 | 1 |
| 60 | 44-A.Bradshaw | NYG | 15 | -0.22 | 0.8 | -0.01 | 0.00 | 42.3 | 163 | 778 | 4.8 | 7 | 21 | 207 | 0 |
| 61 | 25-J.Fargas | OAK | 12 | -0.22 | -16.2 | -0.02 | -0.11 | 35.5 | 129 | 491 | 3.8 | 3 | 17 | 113 | 0 |
| 62 | 27-B.Jacobs | NYG | 14 | -0.27 | -28.6 | -0.02 | -0.12 | 36.3 | 211 | 759 | 3.6 | 4 | 16 | 173 | 1 |
| 63 | 28-D.Ward | TB | 14 | -0.28 | -11.3 | -0.02 | -0.08 | 32.9 | 115 | 414 | 3.6 | 1 | 20 | 150 | 3 |
| 64 | 20-S.Slaton | HST | 11 | -0.31 | -10.4 | -0.03 | -0.05 | 37.4 | 131 | 437 | 3.3 | 3 | 44 | 417 | 4 |
| 65 | 31-J.Lewis | CLV | 9 | -0.31 | -15.8 | -0.03 | -0.10 | 29.5 | 143 | 500 | 3.5 | 0 | 8 | 88 | 0 |
| 66 | 20-D.McFadden | OAK | 12 | -0.36 | -22.9 | -0.03 | -0.15 | 33.1 | 104 | 356 | 3.4 | 1 | 21 | 245 | 0 |
| 67 | 39-W.Parker | PIT | 13 | -0.38 | -5.9 | -0.03 | -0.06 | 40.2 | 98 | 389 | 4.0 | 0 | 6 | 64 | 1 |
| 68 | 26-C.Portis | WAS | 8 | -0.41 | -19.0 | -0.05 | -0.14 | 34.3 | 124 | 494 | 4.0 | 1 | 9 | 57 | 1 |
| 69 | 25-L.White | TEN | 13 | -0.43 | -10.9 | -0.03 | -0.15 | 38.0 | 64 | 222 | 3.5 | 2 | 3 | 14 | 0 |
| 70 | 34-T.Hightower | ARZ | 16 | -0.48 | -17.1 | -0.03 | -0.07 | 40.7 | 143 | 598 | 4.2 | 8 | 63 | 428 | 0 |
| 71 | 29-G.Coffee | SF | 10 | -0.53 | -21.8 | -0.05 | -0.21 | 28.4 | 83 | 226 | 2.7 | 1 | 11 | 76 | 0 |
| 72 | 27-L.Johnson | CIN | 14 | -0.57 | -32.4 | -0.04 | -0.16 | 30.9 | 178 | 562 | 3.2 | 0 | 15 | 80 | 0 |
| 73 | 23-M.Lynch | BUF | 13 | -0.60 | -24.7 | -0.05 | -0.15 | 32.7 | 120 | 450 | 3.8 | 2 | 28 | 179 | 0 |
| 74 | 35-J.Harrison | CLV | 14 | -0.70 | -22.7 | -0.05 | -0.09 | 38.6 | 194 | 862 | 4.4 | 5 | 34 | 220 | 2 |
| 75 | 22-C.Brown | HST | 14 | -0.76 | -20.0 | -0.05 | -0.19 | 38.5 | 79 | 267 | 3.4 | 3 | 16 | 74 | 0 |
| 76 | 27-K.Moreno | DEN | 16 | -0.77 | -28.9 | -0.05 | -0.10 | 41.6 | 247 | 947 | 3.8 | 7 | 28 | 213 | 2 |
| 77 | 39-S.Jackson | SL | 15 | -0.77 | -29.2 | -0.05 | -0.07 | 39.5 | 325 | 1424 | 4.4 | 4 | 50 | 314 | 0 |
| 78 | 22-M.Forte | CHI | 15 | -1.24 | -30.6 | -0.08 | -0.09 | 34.1 | 252 | 905 | 3.6 | 4 | 53 | 446 | 0 |
